CuBr-catalyzed selective oxidation of N-azomethine: highly efficient synthesis of methine-bridged bis-indole compounds.

نویسندگان

  • Jianguo Yang
  • Zhijing Wang
  • Fuyou Pan
  • Yongmin Li
  • Weiliang Bao
چکیده

An efficient CuBr catalyzed cleavage of C-N bonds in the oxidative cross-dehydrogenative-coupling (CDC) of N-benzyl amines with indoles mediated by tert-butyl hydroperoxide (TBHP) was reported. A series of methine-bridged bis-indole derivatives were successfully synthesized under the optimized reaction conditions.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 8 13  شماره 

صفحات  -

تاریخ انتشار 2010